Over at RPGNet, I made an off remark that "who would want to run a game from a pdf?". Naturally enough, a fair number of people got offended and said I'm some kind of luddite and that pdf gaming is the future. I understand economically that many game producers have to go pdf-only, or maybe have a print-on-demand option (I have had only good experiences with Lulu).
But I can't imagine bringing a laptop to the table to run a game. Maybe it would be easier for those who have an iPad, but I don't. And I'd be terrified that someone would spill a soda on my machine. Computers aren't cheap. And trying to look up rules on a computer screen, to me, would take too long. And I'd probably end up with a headache after trying to read too much. Maybe bookmarking helps a bit, but for me, pdfs will never replace real books.